Blood Test To Manage Parkinson’s Nears Final Stages

Blood Test To Manage Parkinson’s Nears Final Stage

( – Medicine is making great strides in treating what ails us, which gives hope to nearly one million people living with Parkinson’s disease in the United States. Researchers have found better ways to manage the disease, and they can even identify the disease much earlier than before. There is even a possible treatment on the horizon. In the meantime, a new blood test is in development to make management of the disease much easier.

The Progression of Parkinson’s Disease

Parkinson’s is a progressive disease that has five stages. But the progression is different for everyone. It can progress at different rates and exhibit different symptoms. One person may have some symptoms that another doesn’t. It really depends on the individual, and that’s what makes progression prediction so difficult.

  • Stage One – Tremors on one side of the body and postural changes, walking issues and difficulties with facial expressions can occur. These symptoms do not interfere with daily life.
  • Stage Two – Tremors on both sides, rigidity, walking problems and posture issues are apparent. Tasks are more difficult, but independent living is still possible.
  • Stage Three – Slow movements, loss of balance and falls are more common. Everyday activities, such as eating and dressing, become difficult. But living alone is still possible.
  • Stage Four – A walker is required and activities are difficult, if not impossible, to perform. Daily care and assistance are needed.
  • Stage Five – It may be impossible to stand or walk. Around-the-clock care is necessary, as the person may be bedridden. Hallucinations and delusions can appear at this stage.

As you can imagine, Parkinson’s requires different levels of care as the disease progresses. But it can be difficult to predict where the disease is going to go next. This is where the new blood test can help.

A New Blood Test Could Predict Progression

About 80% of Parkinson’s patients will develop dementia or cognitive impairment. It is believed that inflammation plays a role in it. Additionally, inflammation has been linked with rapid progression of the disease. This means that people with higher levels of inflammation progress through the stages of the disease much quicker than those with low levels of inflammation.

A new blood test has been developed and is in testing that measures inflammatory and cell senescence biomarkers to help doctors predict how Parkinson’s will progress in individuals. This snapshot in time would enable practitioners to look into the future and make therapeutic decisions based on how the disease will progress and/or react. Currently, they can only rely on clinical symptoms after they appear.

What it Means for Parkinson’s Disease Management

This new blood test could have a huge impact on how Parkinson’s is managed and treated in the future. As new treatments become available, practitioners will be able to better match patients with proper treatment, based on their predicted disease timeline.

It will also help them decide when to start certain treatments or therapies in anticipation of new symptoms. All in all, it will help in treatment planning and may even influence the way future trials of disease-modifying interventions are performed in the future. While some human testing has already been performed, more trials are necessary before the new test can be brought to market. The prospects look bright based on current testing.

If medical professionals can predict how Parkinson’s will progress with each individual, they can better tailor therapies to meet the needs of that individual. This new blood test could give them a glimpse into the future and allow them to anticipate and find solutions for problems before they arise, rather than scramble to catch up once symptoms present themselves.

~Here’s to Your Healthy Pursuits!

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